Kava-kava

A 2008 paper by Thoeringer et. al., published in the Journal of Neural Transmission [1] described a study of 238 adult Caucasian patients recruited from an Anxiety Disorders Outpatient Clinic in Europe presenting various anxiety disorders, including panic disorder, agoraphobia, social phobia and generalized anxiety disorder….

Raining DNA

Depressive and neurotic behaviours have many potential triggers and contributory factors, but few associated genetic variants have been found, most likely due to the large numbers of subjects needed: Genome-Wide Association Studies (GWAS) require large sample sizes to have sufficient…

Opus Training, April 9-10 2016

This has been a wonderful month for attending training and conferences and for reconnecting with so many friends and colleagues. The Opus Pro new software that Dr. D’Adamo designed is phenomenal! The software is cutting edge and user friendly. Those…

A Roster of Opus 23 Algorithms

This is a current list of the multi-snp algorithms currently available in Opus 23. A few titles repeat, for the simple reason that two different algorithms, using different snps or genes, can result in a similar conclusion.  Algorithms can be…

Strobing the tissues

Opus 23 provides many unique opportunities for data integration and visualization. One app that I’ve just been added to the Opus toolbox is STROBE, a new Opus analytic app that allows you drill-down client genomic data by organ, tissue or…

Don't Fall into the Methyl Trap!

Methyl trapping is a situation in which folate becomes trapped and unusable by the body. It is defined as a functional folate deficiency that alters homocysteine metabolism such that folate–dependent resynthesis of methionine is compromised. Methyl trapping was originally described in…

Agency

The Agency app in Opus 23 takes pharmacogenomics to the next level. Relying on the extensive Opus 23 database of published research detailing gene expression data linked to natural products, Agency provides a visual representation of their interactions web. Multiple…