DEVELOPER NOTES

Agency

The Agency app in Opus 23 takes pharmacogenomics to the next level. Relying on the extensive Opus 23 database of published research detailing gene expression data linked to natural products, Agency provides a visual representation of their interactions web. Multiple agents can be displayed, allowing the clinician to synthesis multi-target […]

SuperMogadon

SuperMogadon is a highly flexible search and sort tool that allows you to easily compare the client’s genotype with results from Genome Wide Association Studies* (GWAS) through the Opus 23 Pro database. As you can see there are over 50+ pages of GWAS data in SuperMogadon, which would make grinding […]

MoboCaster

MoboCaster is an Opus 23 Pro informatics app that performs scenario-specific genomic analysis since, as clinicians, that’s pretty much how we think about genomics. The browser screen (above) in MoboCaster lists an overview of several genomic scenarios, such as the HPA Axis, Oxalate Genomics, Phase I Detoxification, etc. that display […]

Ancestry data is a no-go

Initially, I was very excited about the prospect of allowing the import of ancestry.com DNA data into Opus 23. After all, they use the same Illumina technology as 23andMe (although 23andMe apparently have their own unique chip.) Initial testing was promising. Like 23andMe, Ancestry supplies raw data in a basic […]

Microbiome mashup

There has been an explosion of interest in the microbiome. Outfits such as uBiome has made it relatively inexpensive and easy to have your microbiome profiled. These services extract the bacterial DNA out of the sample and identify each of the bacteria that the DNA came from. There appear to […]

Protocol development

Two years ago I developed a software app called SkySaw for use on my teaching shift at the COEGM. SkySaw allows clinicians to structure patient encounters as a linked network (technically a directed acyclic graph). What made this attractive was that these individual networksĀ could be connected together into a great […]

Pearl of an idea

Like most of my coding projects Opus 23 Pro is written primarily in the Perl scripting language. Perl handles most of the basic server-side functions (like disk reading, etc) and sends its output out to the browser via HTML, Javascript, etc. Perl is widely used in bioinformatics, and has been […]

Multi-SNP algorithms

Algorithms are perhaps the most significant and flexible aspect of Opus 23 data. They are usually the easiest result for the non-medical person to understand, because their conclusions are usually simplified statements in everyday language. Algorithms are processed by the LUMEN app in Opus 23 Pro. LUMEN is one of […]