DEVELOPER NOTES

Don’t Fall into the Methyl Trap!

Methyl trapping is a situation in which folate becomes trapped and unusable by the body. It is defined as a functional folate deficiency that alters homocysteine metabolism such that folate–dependent resynthesis of methionine is compromised. Methyl trapping was originally described in Downs Syndrome (trisomy 21) where plasma levels of homocysteine, methionine, […]