The Opus 23 PSYCHIC app allows you to search for natural products known to control gene expression. However, unlike a simple search engine, PSYCHIC is able to crawl up and down the molecular ‘Interactome’ (protein-protein interactions and gene expression data) to determine the upstream and downstream genes that interact with […]
The Agency app in Opus 23 takes pharmacogenomics to the next level. Relying on the extensive Opus 23 database of published research detailing gene expression data linked to natural products, Agency provides a visual representation of their interactions web. Multiple agents can be displayed, allowing the clinician to synthesis multi-target […]
SuperMogadon is a highly flexible search and sort tool that allows you to easily compare the client’s genotype with results from Genome Wide Association Studies* (GWAS) through the Opus 23 Pro database. As you can see there are over 50+ pages of GWAS data in SuperMogadon, which would make grinding […]
MoboCaster is an Opus 23 Pro informatics app that performs scenario-specific genomic analysis since, as clinicians, that’s pretty much how we think about genomics. The browser screen (above) in MoboCaster lists an overview of several genomic scenarios, such as the HPA Axis, Oxalate Genomics, Phase I Detoxification, etc. that display […]
Initially, I was very excited about the prospect of allowing the import of ancestry.com DNA data into Opus 23. After all, they use the same Illumina technology as 23andMe (although 23andMe apparently have their own unique chip.) Initial testing was promising. Like 23andMe, Ancestry supplies raw data in a basic […]
There has been an explosion of interest in the microbiome. Outfits such as uBiome has made it relatively inexpensive and easy to have your microbiome profiled. These services extract the bacterial DNA out of the sample and identify each of the bacteria that the DNA came from. There appear to […]
Two years ago I developed a software app called SkySaw for use on my teaching shift at the COEGM. SkySaw allows clinicians to structure patient encounters as a linked network (technically a directed acyclic graph). What made this attractive was that these individual networks could be connected together into a great […]
Like most of my coding projects Opus 23 Pro is written primarily in the Perl scripting language. Perl handles most of the basic server-side functions (like disk reading, etc) and sends its output out to the browser via HTML, Javascript, etc. Perl is widely used in bioinformatics, and has been […]
I designed Opus 23 Pro to serve two user audiences: the physician who works in the development environment to generate and curate information; and the client, who represents the end-user of that information. Both have widely differing needs and points of reference. One aspect of Opus 23 Pro that I […]
Algorithms are perhaps the most significant and flexible aspect of Opus 23 data. They are usually the easiest result for the non-medical person to understand, because their conclusions are usually simplified statements in everyday language. Algorithms are processed by the LUMEN app in Opus 23 Pro. LUMEN is one of […]
