{"id":164,"date":"2016-01-05T17:04:39","date_gmt":"2016-01-05T22:04:39","guid":{"rendered":"http:\/\/datapunk.net\/opus23blog\/?p=164"},"modified":"2016-01-05T17:17:39","modified_gmt":"2016-01-05T22:17:39","slug":"supermogadon","status":"publish","type":"post","link":"https:\/\/datapunk.net\/opus23blog\/2016\/01\/05\/supermogadon\/","title":{"rendered":"SuperMogadon"},"content":{"rendered":"

SuperMogadon<\/em> is a highly flexible search and sort tool that allows you to easily compare the client’s genotype with results from Genome Wide Association Studies* (GWAS) through the Opus 23 Pro database. <\/p>\n

As you can see there are over 50+ pages of GWAS data in SuperMogadon<\/em>, which would make grinding through the data rather impractical. Like most data displays in Opus 23 that deal with large amounts of data, SuperMogadon<\/em> features a ‘filterable’ display. Type full or partial search terms into the search box at the upper left hand corner and SuperMogadon<\/em> immediately displays only those results. <\/p>\n

Click on the graph icon to display SNP distribution for that pathology or trait as a Manhattan Plot. Click on any column title to sort by that column. <\/p>\n

\"SuperMogadon
SuperMogadon Index Page<\/figcaption><\/figure>\n

Clicking on the blue graph icon in the ‘Show Plot’ column will launch the SuperMogadon<\/em> Manhattan plotter for that disease\/trait.<\/p>\n

TheSuperMogadon<\/em> Viewer is a GWAS Manhattan plotter, a type of scatter chart used to display data with a large number of data-points. Genomic SNP coordinates (marked by chromosome) are displayed along the X-axis, with the negative logarithm of association P-value for the disease or pathology displayed on the Y-axis. Because the strongest associations have the smallest P-values (e.g., 10 \u221215), their negative logarithms will be the greatest (e.g., 15). In the example above, we see the graph for ‘Type II diabetes’ as a GWAS Manhattan plot. <\/p>\n

Client SNP genotypes results are shape and color-coded:<\/p>\n