Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs1799963

Hard Link
rs1799963 is a snp on gene F2 (coagulation factor II (thrombin))

GeneF2 Chromosome number Chromosome position
Alleles (transliterated to +) Minor Allele Minor Allele Frequency
Notation G20210A rs1799963 Clinical significance Orientation (dbSNP) - (negative/reverse strand)
SNP Function
3' UTR variant. Prothrombin F2 prothrombin factor mutation rs3799963 G20210A.
Gene Function
The F2 codes for the protein 'thrombin' (Coagulation factor II).  Prothrombin (coagulation factor II) is cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn  converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Thrombin is the first step of the coagulation cascade which ultimately results in the stemming of blood loss. Mutations in F2 leads to various forms of thrombosis (local coagulation or clotting of the blood in a part of the circulatory system.)  
This SNP is reported by one or more services.


23andme V3

NOT REPORTED




23andme V4

NOT REPORTED




23andme V5

NOT REPORTED




Ancestry DNA

REPORTED




Genos Export for Promethease

NOT REPORTED




DSL/ Opus Chip

REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

CURATED




GWAS Curated

NOT CURATED





MOST RECENT SEARCHES:
rs1024611 () | rs3024496 () | Rs2660 () | rs1800896 (IL10) | rs2069705 () | rs4684847 () | rs1799964 () | rs5743594 () | rs5743795 () | rs5743551 () | rs622502 ()

MOST FREQUENTLY SEARCHED:
rs429358 (APOE) | rs9939609 (FTO) | rs1801181 (CBS) | rs1799941 (SHBG) | rs1801133 (MTHFR) | rs2187668 (HLA-DQA1) | rs4680 (COMT) | rs6025 (F5) | rs20541 (IL13) | rs2569191 (CD14) | rs2235544 (DIO1)








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